⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449448 | 0.89 | — | — | |
| SCHEMBL248510 | 0.85 | — | — | |
| SCHEMBL7458771 | 0.78 | GNAI3 (0.41) | — | |
| SCHEMBL42566 | 0.77 | — | — | |
| SCHEMBL84808 | 0.75 | CHRNA7 (0.48) | — | |
| SCHEMBL577415 | 0.75 | CHRNA7 (0.48) | — | |
| SCHEMBL6657817 | 0.75 | CHRNA7 (0.48) | — | |
| SCHEMBL577052 | 0.75 | CHRNA7 (0.48) | — | |
| SCHEMBL262312 | 0.75 | — | — | |
| Trimethylammonium SCHEMBL31097229 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3230 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| WO-2024099337-A1 | THIADIAZOLYL DERIVATIVES, COMPOSITIONS, AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-16 | — | — | WO | claimed |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-05-16 | — | — | US | claimed |
| EP-3498716-B1 | SULFONYL BEARING THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATION AS ANTI-CANCER AGENT | UNIV XIAMEN (CN) | 2024-04-17 | — | — | EP | claimed |
| US-20240075136-A1 | COMBINATION THERAPIES | NOVARTIS AG (CH) | 2024-03-07 | — | — | US | claimed |
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| CN-113549018-B | Protein kinase inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | claimed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | claimed |
| EP-4320124-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2024-02-14 | — | — | EP | claimed |
| CN-115894486-B | Hydrogenated pyridoquinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| US-4363816-A | TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-14 | — | — | US | claimed |
| US-4362727-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS, NEUROLEPTICS, ANTIPARKINSON | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-07 | — | — | US | claimed |
| EP-0050212-A1 | 5-Substituted-9-cyane-methylene-dithieno(3,4-b:4',3'-e) azepines, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1982-04-28 | — | — | EP | claimed |
| EP-0035711-A2 | 10-Substituted-5-cyanomethylene-dibenzo-(a,d)cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0035714-A2 | 10-Substituted-5-cyanomethylene-10,11-dihydro-dibenzo-(a,d)-cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0024582-A1 | Benzodiazepinones, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-11 | — | — | EP | claimed |
| EP-0019172-A1 | 6-Substituted 11-alkylene-morphantridines, process for preparing them and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | claimed |
| US-4235775-A | Triazolobenzodiazepine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-11-25 | — | — | US | claimed |
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |