⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42921 | 0.85 | — | — | |
| SCHEMBL449448 | 0.76 | — | — | |
| SCHEMBL8204680 | 0.76 | GNAI3 (0.46) | — | |
| SCHEMBL1938163 | 0.69 | — | — | |
| SCHEMBL42566 | 0.69 | — | — | |
| SCHEMBL262312 | 0.66 | — | — | |
| SCHEMBL577052 | 0.66 | CHRNA7 (0.48) | — | |
| SCHEMBL6657817 | 0.66 | CHRNA7 (0.48) | — | |
| SCHEMBL577415 | 0.66 | CHRNA7 (0.48) | — | |
| SCHEMBL84808 | 0.66 | CHRNA7 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | claimed |
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | disclosed |
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2000032586-A1 | METHOD FOR PREPARING 3-CHROMENE DERIVATIVES, USE OF SAID DERIVATIVES FOR PREPARING THIAZOLIDINONES | RHODIA CHIMIE (FR) | 2000-06-08 | — | — | WO | disclosed |
| WO-1999006392-A1 | METHOD FOR PREPARING 2H-1 BENZOPYRANES AND SYNTHESIS INTERMEDIATES | RHODIA CHIMIE (FR) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998041518-A1 | METHOD FOR PREPARING 2H-1 BENZOPYRANES | RHODIA CHIMIE (FR) | 1998-09-24 | — | — | WO | disclosed |
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |
| US-4108994-A | 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS | ROUSSEL UCLAF (FR) | 1978-08-22 | — | — | US | disclosed |