Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.74 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL6583530 | 0.91 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Acetic Acid SCHEMBL27357071 | 0.89 | ALDH1A1 (0.71) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Acetic Acid SCHEMBL28299908 | 0.89 | ALDH1A1 (0.71) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Benzene SCHEMBL22289542 | 0.89 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL9029 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL4941999 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL29413841 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Benzoic Acid SCHEMBL27454196 | 0.86 | TSHR (0.65) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Propionic Acid SCHEMBL30668813 | 0.84 | ALDH1A1 (0.63) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Hydroxyamine SCHEMBL10337879 | 0.84 | ALDH1A1 (0.85) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217001-B2 | Modification of feeding behavior | IMPERIAL INNOVATIONS LIMITED | 2012-07-10 | — | — | US | disclosed |
| US-20090209461-A1 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209461-A1 | MODIFICATION OF FEEDING BEHAVIOR | NPY4R, NPY5R, NPY2R | ALDH1A1 4693/4885CYP3A4 4655/4885HPGD 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.