Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 12/20 | 0.39 |
| ▸ | NOS1 | P29475 | 12/20 | 0.39 |
| ▸ | NOS2 | P35228 | 12/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018111 | 0.91 | NOS1 (0.44) | NOS3NOS1NOS2CHRNB4CHRNA3 | |
| SCHEMBL4282777 | 0.89 | IRAK4 (0.39) | NOS3NOS1NOS2CHEK2PRKCZ | |
| SCHEMBL4012567 | 0.86 | NOS3 (0.38) | NOS3NOS1NOS2CHEK2PRKCZ | |
| SCHEMBL3404577 | 0.85 | CHRNB4 (0.39) | NOS3NOS1NOS2CHEK2PRKCZ | |
| SCHEMBL4292393 | 0.84 | NOS3 (0.40) | NOS3NOS1NOS2CHEK2PRKCZ | |
| SCHEMBL419970 | 0.82 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL221745 | 0.82 | FPR2 (0.39) | NOS3NOS1NOS2CHRNB4CHRNA3 | |
| SCHEMBL252496 | 0.79 | NOS1 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL6582950 | 0.79 | NOS3 (0.62) | NOS3NOS1NOS2 | |
| SCHEMBL222427 | 0.77 | NOS3 (0.48) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158646-A1 | THERAPEUTIC COMPUNDS AND RELATED METHODS OF USE | ELIXIR PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |