SCHEMBL429314

SCHEMBL429314

c1ccc(-c2cccc(-c3cccc4c3oc3c(-c5ccccc5-c5ccccc5-c5cccc6c5oc5c(-c7cccc(-c8ccccc8)c7)cccc56)cccc34)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 11/20 0.50
ALOX5 P09917 2/20 0.47
PLA2G2A P14555 1/20 0.41
PLA2G4A P47712 1/20 0.41
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
PIK3CD O00329 2/20 0.40
PIK3CA P42336 2/20 0.40
PIK3CB P42338 2/20 0.40
PIK3CG P48736 2/20 0.40
KDM4E B2RXH2 2/20 0.40
BRD4 O60885 2/20 0.40
BRD2 P25440 2/20 0.40
BRD3 Q15059 2/20 0.40
PDE2A O00408 1/20 0.40
PIK3C2A O00443 1/20 0.40
PIK3R2 O00459 1/20 0.40
PIK3C2B O00750 1/20 0.40
PDE5A O76074 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21157904 0.94 PRKDC (0.51) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL17057203 0.94 ALOX5 (0.53) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL1637685 0.93 PRKDC (0.50) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL1636141 0.93 PRKDC (0.50) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22175039 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22174960 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22174961 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22174959 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22174894 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1
SCHEMBL22182840 0.91 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406893-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406893-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20140299861-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2014-10-09 US disclosed
US-20140299861-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2014-10-09 US disclosed
US-8790794-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-29 US disclosed
US-8790794-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-29 US disclosed
US-20120061651-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-15 US disclosed
US-20120061651-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120061651-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CYP2J2, CYP1A1, CRY1 PRKDC 4868/4885ALOX5 2991/4885PLA2G2A 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.