SCHEMBL1636141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637685	1.00	PRKDC (0.50)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL17057203	0.94	ALOX5 (0.53)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL21157904	0.94	PRKDC (0.51)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL1635697	0.93	ALOX5 (0.44)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL429314	0.93	PRKDC (0.50)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL24090397	0.92	ALOX5 (0.60)	PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
	SCHEMBL17057281	0.91	ALOX5 (0.48)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL17057263	0.91	ALOX5 (0.48)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL17057308	0.91	ALOX5 (0.48)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1
	SCHEMBL1635705	0.91	ALOX5 (0.46)	PRKDCALOX5PLA2G2APLA2G4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.