SCHEMBL4293800

SCHEMBL4293800

O=C(OCC1c2ccccc2-c2ccccc21)Oc1cc[c]cc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FABP5 Q01469 3/20 0.48
▸ FABP7 O15540 2/20 0.48
▸ KMT2A Q03164 2/20 0.46
▸ EPHX2 P34913 1/20 0.43
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CASP3 P42574 2/20 0.37
▸ DPP8 Q6V1X1 1/20 0.36
▸ DPP9 Q86TI2 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27143076 0.88 FABP5 (0.52) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL14590853 0.82 FABP5 (0.47) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL44676 0.81 KMT2A (0.58) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL14099780 0.81 CYP1A2 (0.47) FABP5FABP7KMT2AEPHX2
SCHEMBL9647974 0.80 KMT2A (0.43) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL9355666 0.80 KMT2A (0.43) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL15058849 0.78 KMT2A (0.55) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL9225108 0.78 GAA (0.49) FABP5FABP7KMT2AEPHX2
SCHEMBL9225114 0.77 FABP5 (0.44) FABP5FABP7KMT2AEPHX2
SCHEMBL29996541 0.75 KMT2A (0.47) FABP5FABP7KMT2AEPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076294-B2 Collagen-related peptides and uses thereof ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC. (US) 2011-12-13 — — US disclosed
US-20090299034-A1 Collagen-related peptides JANSSEN PHARMACEUTICA, N.V. (BE) 2009-12-03 — — US disclosed
US-20090068246-A1 COLLAGEN-RELATED PEPTIDES AND USES THEREOF ETHICON, INC. 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299034-A1 Collagen-related peptides COL14A1, COL2A1, COL1A1 FABP5 450/4885FABP7 906/4885KMT2A 4250/4885
US-20090068246-A1 COLLAGEN-RELATED PEPTIDES AND USES THEREOF COL14A1, COL2A1, COL1A1 FABP5 559/4885FABP7 953/4885KMT2A 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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