Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225114 | 0.86 | FABP5 (0.44) | GAAFABP5KMT2ANPC1FABP7 | |
| SCHEMBL14099780 | 0.86 | CYP1A2 (0.47) | GAAFABP5KMT2ANPC1FABP7 | |
| SCHEMBL14590853 | 0.84 | FABP5 (0.47) | FABP5KMT2AFABP7HTTEPHX2 | |
| SCHEMBL27143076 | 0.82 | FABP5 (0.52) | FABP5KMT2AFABP7EPHX2 | |
| SCHEMBL9220926 | 0.82 | EPHX2 (0.56) | GAAKMT2ANPC1MDM2ALDH1A1 | |
| SCHEMBL9355666 | 0.80 | KMT2A (0.43) | FABP5KMT2AFABP7EPHX2 | |
| SCHEMBL9647974 | 0.80 | KMT2A (0.43) | FABP5KMT2AFABP7MDM2EPHX2 | |
| SCHEMBL4293800 | 0.78 | FABP5 (0.48) | FABP5KMT2AFABP7EPHX2 | |
| SCHEMBL5337013 | 0.78 | ALDH1A1 (0.46) | GAAFABP5KMT2AFABP7MDM2 | |
| SCHEMBL60475 | 0.77 | FABP5 (0.45) | GAAFABP5KMT2AFABP7MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410068-A | Protecting groups for natural products | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0424819-B1 | Reversible modification of biological compounds for detection, separation and purification thereof | MILLIPORE CORP (US) | 1994-12-28 | — | — | EP | disclosed |