Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | QDPR | P09417 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | PTAFR | P25105 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655297 | 0.93 | PDE4B (0.36) | HTR2CQDPRPDE4APDE4BPDE4C | |
| SCHEMBL23706025 | 0.85 | PTPN1 (0.30) | — | |
| SCHEMBL15352997 | 0.79 | PDE4A (0.32) | PDE4ADRD2 | |
| SCHEMBL15353176 | 0.79 | DHODH (0.32) | HTR1AADRA1DHIF1A | |
| SCHEMBL15353303 | 0.78 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28241529 | 0.76 | HTR2C (0.33) | HTR2C | |
| SCHEMBL28241525 | 0.76 | — | — | |
| SCHEMBL25412227 | 0.75 | TSHR (0.47) | — | |
| SCHEMBL458962 | 0.72 | HTR2C (0.37) | HTR2CQDPRESR2 | |
| SCHEMBL15352612 | 0.72 | ESR2 (0.34) | HTR2CQDPRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| WO-2021078120-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-04-29 | — | — | WO | claimed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | claimed |
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | claimed |
| US-20160037776-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | claimed |
| EP-2595995-B1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2015-11-25 | — | — | EP | claimed |
| EP-2595995-A1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2013-05-29 | — | — | EP | claimed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | claimed |
| WO-2012010633-A1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2012-01-26 | — | — | WO | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| WO-2021078120-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-04-29 | — | — | WO | disclosed |
| US-10986839-B2 | Substituted oxadiazoles for combating phytopathogenic fungi | BASF SE (DE) | 2021-04-27 | — | — | US | disclosed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| EP-2595995-A1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010633-A1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2011-05-05 | — | — | US | disclosed |
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158426-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HTR2C 1138/4885QDPR 234/4885PDE4A 524/4885 |
| US-20160037776-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HTR2C 1138/4885QDPR 234/4885PDE4A 524/4885 |
| US-20110105463-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | GPR52, CD22, CD4 | HTR2C 889/4885QDPR 428/4885PDE4A 1478/4885 |
| US-10986839-B2 | Substituted oxadiazoles for combating phytopathogenic fungi | CYP51A1, ERG28, DPM1 | HTR2C 3996/4885QDPR 2263/4885PDE4A 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.