Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285970 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1KMT2AGAAHCRTR1 | |
| SCHEMBL4290686 | 0.84 | ENPP2 (0.43) | ALDH1A1HCRTR1HCRTR2TEAD1TEAD3 | |
| SCHEMBL4294643 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL3494366 | 0.82 | TEAD1 (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4285558 | 0.82 | HRH3 (0.45) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4289699 | 0.82 | MAOB (0.45) | ALDH1A1KMT2AMEN1HCRTR1HCRTR2 | |
| SCHEMBL4292747 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4287625 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL4295458 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL4286140 | 0.80 | HCRTR1 (0.44) | KDM4EALDH1A1KMT2AMAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156612-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | KDM4E 760/4885ALDH1A1 388/4885KMT2A 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.