SCHEMBL7515231

SCHEMBL7515231

Nc1ccc(-c2c(Cl)cc(N)c(N)c2N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.40
ALDH1A1 P00352 6/20 0.40
TSHR P16473 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
TP53 P04637 2/20 0.40
MAPK1 P28482 1/20 0.40
GAA P10253 3/20 0.39
HSD17B10 Q99714 4/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HPGD P15428 3/20 0.34
ESR2 Q92731 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
RECQL P46063 1/20 0.34
MEN1 O00255 3/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4294687 0.80 TDP1 (0.46) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL9789843 0.78 AHR (0.48) CYP3A4ALDH1A1TSHRTDP1TP53
Hydrochloric Acid SCHEMBL29118192 0.76 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL4847168 0.71 CYP3A4 (0.59) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL10609852 0.71 THRB (0.43) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL6020612 0.69 CYP3A4 (0.62) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL31163138 0.69 CYP3A4 (0.55) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL14055104 0.69 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL3821946 0.69 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1TP53
SCHEMBL29450595 0.68 CYP3A4 (0.71) CYP3A4ALDH1A1TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002012898-A1 AN IMPROVED PROCESS FOR PREPARATION OF IMMUNOCHEMICAL COMPLEX USEFUL FOR PATHOGEN DETECTION AND DETERMINATION OF THEIR ANTIBIOTIC SENSITIVITY UNIVERSITY OF PUNE (IN) 2002-02-14 WO claimed
WO-2002012898-A1 AN IMPROVED PROCESS FOR PREPARATION OF IMMUNOCHEMICAL COMPLEX USEFUL FOR PATHOGEN DETECTION AND DETERMINATION OF THEIR ANTIBIOTIC SENSITIVITY UNIVERSITY OF PUNE (IN) 2002-02-14 WO disclosed