Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398 | 0.81 | MAPK1 (0.36) | LMNAALDH1A1CYP2D6CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL1295227 | 0.79 | MAPK1 (0.35) | LMNAALDH1A1CYP2D6SLC6A2TAAR1 | |
| SCHEMBL30367101 | 0.79 | MAPK1 (0.35) | LMNAALDH1A1CYP2D6SLC6A2TAAR1 | |
| Phosphoric Acid SCHEMBL28944728 | 0.74 | TSHR (0.41) | ALDH1A1ALOX15 | |
| SCHEMBL27535279 | 0.71 | TAAR1 (0.47) | LMNACYP1A2KDM4EAGTR1RIPK1 | |
| Toluene SCHEMBL11058611 | 0.70 | LMNA (0.55) | LMNACYP1A2KDM4EAGTR1ALDH1A1 | |
| Glycerin SCHEMBL27483108 | 0.69 | KCNN4 (0.46) | LMNACYP1A2KDM4EAGTR1ALDH1A1 | |
| Toluene SCHEMBL11701931 | 0.69 | LMNA (0.52) | LMNACYP1A2KDM4EAGTR1ALDH1A1 | |
| Phenol SCHEMBL28128789 | 0.69 | CA12 (0.52) | LMNACYP1A2KDM4EAGTR1ALDH1A1 | |
| Glycerin SCHEMBL28239880 | 0.68 | LMNA (0.64) | LMNACYP1A2KDM4EAGTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221684-A1 | Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221684-A1 | Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof | ANXA6, STING1, ADM2 | LMNA 967/4885CYP1A2 4706/4885KDM4E 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.