SCHEMBL18398

SCHEMBL18398

CC(C)(C)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 4/20 0.33
TAAR1 Q96RJ0 2/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
ALOX15 P16050 1/20 0.33
SLC6A2 P23975 1/20 0.33
ESR1 P03372 3/20 0.32
ESR2 Q92731 3/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
KCNN4 O15554 2/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1295227 0.97 MAPK1 (0.35) MAPK1ALDH1A1TAAR1TSHRLMNA
SCHEMBL30367101 0.97 MAPK1 (0.35) MAPK1ALDH1A1TAAR1TSHRLMNA
Isobutane SCHEMBL28190489 0.84 CYP1A2 (0.37) ALDH1A1TSHRLMNACYP3A4KMT2A
Glycerin SCHEMBL4294890 0.81 LMNA (0.36) ALDH1A1TAAR1LMNAALOX15SLC6A2
Trifluoromethanesulfonic Acid SCHEMBL28718989 0.79 HSD11B1 (0.37) ALDH1A1TSHRLMNACYP3A4KMT2A
SCHEMBL5613562 0.78 MAPK1 (0.33) MAPK1ALDH1A1TAAR1TSHRLMNA
SCHEMBL28629155 0.78 ALDH1A1 (0.39) ALDH1A1TSHRLMNAALOX15ESR1
SCHEMBL8381893 0.77 ALDH1A1 (0.37) MAPK1ALDH1A1TAAR1TSHRLMNA
SCHEMBL3691011 0.77 MAPK1 (0.36) MAPK1ALDH1A1TAAR1TSHRLMNA
SCHEMBL1494198 0.74 ALDH1A1 (0.37) MAPK1ALDH1A1TAAR1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 37919 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229145-B Industrial chemical preparation method of 1, 2-diglyceride Guangzhou Baiyunshan Hanfang Modern Pharmaceutical Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122071504-A Oxime-decorated glycosyl thioether, and preparation method and application thereof 四川大学华西医院 2026-05-22 CN claimed
CN-121736022-B Preparation method of locked nucleic acid intermediate 北京瑞博奥医药科技有限公司 2026-05-12 CN claimed
US-12559514-B2 Synthesis of fluorinated nucleotides MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
US-20260049097-A1 LOW DIELECTRIC COMPOUND, MANUFACTURING METHOD THEREOF, RESIN COMPOSITION, AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MATERIAL (ZHONGSHAN) CO., LTD. (CN) 2026-02-19 US claimed
CN-116867789-B Preparation method of irinotecan derivative and intermediate thereof 上海复旦张江生物医药股份有限公司 2025-06-24 CN claimed
WO-2025125426-A1 COMPOSITION AND SOLID ELECTROLYTE ARKEMA FRANCE (FR) 2025-06-19 WO claimed
WO-2025125489-A1 TITLE: COMPOSITION AND SOLID ELECTROLYTE ARKEMA FRANCE (FR) 2025-06-19 WO claimed
CN-119661614-A Indolocarbazole glycoside alkaloid, preparation method thereof and application thereof in anti-leukemia drugs 中国海洋大学 2025-03-21 CN claimed
CN-119504759-A 2, 3-Dihydro-quinazolinone compound and preparation method and application thereof 杭州医学院 2025-02-25 CN claimed
US-4430497-A PRESENCE OF LEWIS ACID GRUENENTHAL GMBH (DE) 1984-02-07 US claimed
US-4424374-A Bicycloheptane derivatives MAY & BAKER LIMITED (GB) 1984-01-03 US claimed
EP-0090340-A1 Process for preparation of optically active 4-(2-Hydroxyethyl)-2-azetidinone KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-10-05 EP claimed
US-4356120-A 3-(1-Hydroxyethyl)-4-(but-2-ene)-azetidin-2-one and derivatives MERCK & CO., INC. (US) 1982-10-26 US claimed
US-4296035-A Total synthesis of the utero-evacuant substance d,l-zoapatanol ORTHO PHARMACEUTICAL CORPORATION (US) 1981-10-20 US claimed
US-4290947-A Process for the preparation of thienamycin and intermediates MERCK & CO., INC. (US) 1981-09-22 US claimed
US-4273709-A Process for the preparation of thienamycin and intermediates MERCK & CO., INC. (US) 1981-06-16 US claimed
EP-0021775-A1 Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo(3.2.1)octane-1-acetic acid and intermediates ORTHO PHARMACEUTICAL CORPORATION (US) 1981-01-07 EP claimed
US-4237055-A Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid ORTHO PHARMACEUTICAL CORPORATION (US) 1980-12-02 US claimed
US-4237053-A Total synthesis of the utero-evacuant substance d,l-zoapatanol ORTHO PHARMACEUTICAL CORPORATION (US) 1980-12-02 US claimed