SCHEMBL4295316

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31363216	0.89	HSD17B10 (0.37)	L3MBTL1CA12CA1CA2CA7
	SCHEMBL20803212	0.89	HSD17B10 (0.37)	L3MBTL1CA12CA1CA2CA7
	SCHEMBL10333314	0.84	MAPT (0.44)	L3MBTL1CA12CA1CA2CA7
	SCHEMBL10852579	0.83	KMT2A (0.48)	L3MBTL1ALDH1A1KDM4EGAAGLA
	SCHEMBL2963304	0.83	FFAR4 (0.46)	L3MBTL1CA12CA1CA2CA7
	SCHEMBL2471344	0.83	NR4A2 (0.43)	L3MBTL1CA12CA1CA2CA7
	SCHEMBL2473180	0.83	ABL1 (0.51)	L3MBTL1SLC6A3ALDH1A1MAPTHPGD
	SCHEMBL31325341	0.80	KDM4E (0.47)	CA12CA1CA2CA7CA9
	SCHEMBL7759388	0.79	SLC6A3 (0.59)	L3MBTL1SLC6A3ALDH1A1KDM4EGAA
	SCHEMBL9814755	0.79	TDP1 (0.49)	ALDH1A1KDM4EGAAGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.