Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623533 | 0.75 | KMT2A (0.50) | CYP1A2KMT2AADORA1TP53SMN1; SMN2 | |
| SCHEMBL4292120 | 0.74 | OPRD1 (0.43) | MGLLPLA2G7ABHD6CYP1A2KMT2A | |
| SCHEMBL4753615 | 0.73 | HDAC8 (0.41) | MGLLPLA2G7ABHD6HSD17B10P2RY12 | |
| SCHEMBL12777940 | 0.72 | KMT2A (0.59) | HSD17B10KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL2524460 | 0.71 | KMT2A (0.46) | CYP1A2KMT2ALMNAALDH1A1ADORA2A | |
| SCHEMBL17261487 | 0.71 | MAPT (0.47) | HSD17B10KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL11621690 | 0.70 | KMT2A (0.45) | KMT2AALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL17261561 | 0.70 | KMT2A (0.41) | CYP1A2KMT2ALMNAALDH1A1ADORA1 | |
| SCHEMBL21323392 | 0.70 | KMT2A (0.55) | HSD17B10KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL17261514 | 0.69 | EPHX2 (0.43) | CYP1A2KMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | MGLL 2197/4885PLA2G7 1725/4885ABHD6 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.