Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.41 |
| ▸ | TSHR | P16473 | 14/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.41 |
| ▸ | USP2 | O75604 | 10/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.34 |
| ▸ | CASP1 | P29466 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | CASP7 | P55210 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297396 | 0.77 | USP2 (0.31) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL2799084 | 0.75 | ALDH1A1 (0.40) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL4143815 | 0.75 | CYP1A2 (0.39) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL2512106 | 0.75 | KCNH2 (0.42) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL4144852 | 0.74 | ALDH1A1 (0.40) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL19212698 | 0.74 | GGPS1 (0.35) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL3520140 | 0.72 | KCNH2 (0.41) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL12090831 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 | |
| SCHEMBL4302268 | 0.69 | PRPS1 (0.33) | — | |
| SCHEMBL4141389 | 0.69 | CYP1A2 (0.36) | CYP1A2CYP3A4TSHRALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071592-B2 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2011-12-06 | — | — | US | disclosed |
| US-20090270374-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | disclosed |
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270374-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | ETFA, NQO2, GNAQ | CYP1A2 1854/4885CYP3A4 704/4885TSHR 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.