Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550473 | 0.87 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL4694851 | 0.85 | CRHR1 (0.46) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL19709408 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL957652 | 0.79 | CYP3A4 (0.40) | ALDH1A1CYP3A4CRHR1CYP1A2 | |
| SCHEMBL11403757 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL1119927 | 0.77 | CA2 (0.56) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL7827443 | 0.76 | LCK (0.52) | ALDH1A1CYP3A4POLBL3MBTL1NPC1 | |
| SCHEMBL31125235 | 0.76 | LCK (0.52) | ALDH1A1CYP3A4POLBL3MBTL1NPC1 | |
| SCHEMBL9173991 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 | |
| SCHEMBL701066 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP1A1CYP1B1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117534545-A | Compound for treating Alzheimer's disease based on artificial intelligence design, preparation method and medical application thereof | 东北大学 | 2024-02-09 | — | — | CN | disclosed |
| EP-3504261-B1 | FLAME-RETARDED POLYAMIDE COMPOSITION | ICL IP AMERICA INC (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116514771-A | Carboxylic acid compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2021224818-A1 | ISOINDOLONE COMPOUNDS AS HPK1 INHIBITORS | PFIZER INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021224818-A1 | ISOINDOLONE COMPOUNDS AS HPK1 INHIBITORS | PFIZER INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2018044664-A1 | FLAME-RETARDED POLYAMIDE COMPOSITION | ICL-IP AMERICA INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| WO-2018026621-A1 | FLAME-RETARDED POLYESTER COMPOSITION | ICL-IP AMERICA INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| US-20160340498-A1 | FLAME-RETARDED POLYOLEFIN POLYMER COMPOSITION WITH REDUCED ANTIMONY TRIOXIDE CONTENT | ICL-IP AMERICA INC. (US) | 2016-11-24 | — | — | US | disclosed |
| US-20160340498-A1 | FLAME-RETARDED POLYOLEFIN POLYMER COMPOSITION WITH REDUCED ANTIMONY TRIOXIDE CONTENT | ICL-IP AMERICA INC. (US) | 2016-11-24 | — | — | US | disclosed |
| US-20060211727-A1 | Novel compounds | GLAXOSMITHKLINE LLC | 2006-09-21 | — | — | US | disclosed |
| US-6809199-B2 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | MERCK & CO., INC. | 2004-10-26 | — | — | US | disclosed |
| EP-1345603-A4 | (HALO-BENZO CARBONYL)HETEROCYCLO FUSED PHENYL P38 KINASE INHIBITING AGENTS | MERCK & CO INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1345603-A1 | (HALO-BENZO CARBONYL)HETEROCYCLO FUSED PHENYL P38 KINASE INHIBITING AGENTS | Merck & Co., Inc. (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002058695-A9 | (HALO-BENZO CARBONYL)HETEROCYCLO FUSED PHENYL P38 KINASE INHIBITING AGENTS | MERCK & CO INC (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030092712-A1 | (Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents | MERCK SHARP & DOHME CORP. | 2003-05-15 | — | — | US | disclosed |
| US-20030032779-A1 | Estrogen receptor ligands | OHMAN LARS (SE) | 2003-02-13 | — | — | US | disclosed |
| WO-2002058695-A1 | (HALO-BENZO CARBONYL)HETEROCYCLO FUSED PHENYL P38 KINASE INHIBITING AGENTS | MERCK & CO., INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-0980386-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998056812-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 1998-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092712-A1 | (Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents | MAPK1, MAPK7, MAPKAPK2 | ALDH1A1 867/4885CYP3A4 2923/4885CYP1A1 776/4885 |
| US-20030032779-A1 | Estrogen receptor ligands | ESR1, ESRRB, GPER1 | ALDH1A1 2183/4885CYP3A4 990/4885CYP1A1 965/4885 |
| US-20060211727-A1 | Novel compounds | MAPKAPK2, CREBBP, MAPK1 | ALDH1A1 3499/4885CYP3A4 2823/4885CYP1A1 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.