SCHEMBL4297890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4303587	0.83	L3MBTL1 (0.37)	KDM4EHPGDHTR2CHTR2BHTR2A
	SCHEMBL27724756	0.80	L3MBTL1 (0.47)	KDM4EHPGDKMT2AGRM2TDP1
	SCHEMBL23723740	0.79	HTR2C (0.41)	KDM4EHPGDHTR2CHTR2BHTR2A
	SCHEMBL4300393	0.79	GNRHR (0.38)	KDM4EHPGDHTR2CHTR2BHTR2A
	SCHEMBL4305497	0.79	HTR2C (0.40)	KDM4EHPGDHTR2CHTR2BHTR2A
	SCHEMBL2929463	0.77	HTT (0.40)	KDM4EHPGDHTTKMT2AGRM2
	SCHEMBL4299690	0.77	HTR2A (0.35)	HTR2CHTR2BHTR2AGRM2
	SCHEMBL4302346	0.77	MAPK1 (0.46)	KDM4EHPGDHTR2CHTR2BHTR2A
	SCHEMBL22732575	0.76	JAK2 (0.38)	KDM4EHPGDHTTKMT2ARET
	SCHEMBL10300147	0.76	HTR2C (0.38)	KDM4EHPGDHTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.