Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KIF5B | P33176 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233394 | 0.83 | MAPT (0.41) | GAAMAPTKDM4EHTTKMT2A | |
| SCHEMBL25797921 | 0.82 | L3MBTL1 (0.39) | JAK2LMNAGAAMAPTIDO1 | |
| SCHEMBL25797857 | 0.82 | L3MBTL1 (0.39) | JAK2LMNAGAAMAPTIDO1 | |
| SCHEMBL1243321 | 0.81 | ESR1 (0.48) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10335833 | 0.81 | PDE4D (0.41) | GAAMAPTKDM4EHTTKMT2A | |
| SCHEMBL28038952 | 0.80 | ALDH1A1 (0.46) | KDM4EKMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL423475 | 0.80 | ALDH1A1 (0.46) | KDM4EKMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL9419349 | 0.80 | ESR1 (0.48) | JAK2LMNAMAPTKMT2AHPGD | |
| SCHEMBL29362239 | 0.80 | ESR1 (0.48) | JAK2LMNAMAPTKMT2AHPGD | |
| SCHEMBL9419297 | 0.79 | ESR1 (0.50) | JAK2LMNAMAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200377796-A1 | Negative Dielectric Anisotropic Liquid Crystal Compound, Process For Preparing The Same, And Use Thereof | DAILY-XIANHUA OPTOELECTRONICS MATERIALS CO., LTD. (TW) | 2020-12-03 | — | — | US | disclosed |