Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292826 | 0.85 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL4294973 | 0.84 | MGLL (0.40) | L3MBTL1ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL4752309 | 0.83 | PPARG (0.48) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4295179 | 0.83 | KDM4E (0.44) | L3MBTL1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL4288154 | 0.82 | CPS1 (0.52) | L3MBTL1ALDH1A1 | |
| SCHEMBL4752095 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDSMN1; SMN2POLBGAA | |
| SCHEMBL1091884 | 0.77 | KCNQ3 (0.53) | SLC6A9ALDH1A1HPGDMAPTPOLB | |
| SCHEMBL4293508 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4301342 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL30108554 | 0.74 | HTT (0.49) | ALDH1A1MAPTSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | L3MBTL1 3597/4885SLC6A9 357/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.