Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121857 | 0.90 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4123470 | 0.87 | ALDH1A1 (0.42) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4119617 | 0.86 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4123181 | 0.86 | TAS1R3 (0.42) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4123383 | 0.86 | TAS1R3 (0.43) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4111042 | 0.85 | TSHR (0.42) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4123362 | 0.85 | ALDH1A1 (0.44) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4112997 | 0.84 | TAS1R3 (0.39) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4123165 | 0.84 | KDM4E (0.42) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4122265 | 0.84 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239839-A1 | RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20070129348-A1 | Receptor antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1623710-A1 | RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239839-A1 | RECEPTOR ANTAGONIST | FSHR, NR0B2, NR4A3 | TAS1R3 470/4885TAS1R1 780/4885ALDH1A1 2966/4885 |
| US-20070129348-A1 | Receptor antagonist | FSHR, NR0B2, NR4A3 | TAS1R3 470/4885TAS1R1 780/4885ALDH1A1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.