Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28887683 | 0.98 | KDM4E (0.40) | KDM4EKMT2AALDH1A1GAAMAPT | |
| Iodide SCHEMBL29405935 | 0.98 | KDM4E (0.40) | KDM4EKMT2AALDH1A1GAAMAPT | |
| Iodide SCHEMBL10811829 | 0.87 | ALDH1A1 (0.39) | KDM4EKMT2AALDH1A1GAAHTR3E | |
| SCHEMBL30293250 | 0.84 | GSK3A (0.42) | KDM4EALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL28426315 | 0.84 | BRD4 (0.38) | KDM4EKMT2AALDH1A1GAALMNA | |
| SCHEMBL17068087 | 0.79 | MEN1 (0.42) | KDM4EKMT2AALDH1A1GAAMAPT | |
| Iodide SCHEMBL30293255 | 0.79 | LMNA (0.39) | KDM4EKMT2AALDH1A1GAAHTR3E | |
| SCHEMBL28611007 | 0.78 | KDM4E (0.36) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL3698883 | 0.78 | CA12 (0.37) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL29690406 | 0.76 | NOTUM (0.34) | KDM4EKMT2AALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090307791-A1 | CALCIUM-ACTIVATED CHLORIDE CHANNEL AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-10 | — | — | US | disclosed |