SCHEMBL28611007

SCHEMBL28611007

CCNN1CC=Cc2cc(OC)ccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPT P10636 2/20 0.33
ALOX12 P18054 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
TSHR P16473 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
USP2 O75604 1/20 0.32
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299024 0.78 KDM4E (0.41) KDM4EALDH1A1GAAKMT2ACYP1A2
Iodide SCHEMBL29405935 0.77 KDM4E (0.40) KDM4EALDH1A1GAAKMT2ACYP1A2
Iodide SCHEMBL28887683 0.77 KDM4E (0.40) KDM4EALDH1A1GAAKMT2ACYP1A2
Iodide SCHEMBL30293255 0.75 LMNA (0.39) KDM4EALDH1A1GAAKMT2ACYP1A2
SCHEMBL3698883 0.74 CA12 (0.37) KDM4EALDH1A1GAAKMT2ACYP1A2
SCHEMBL28426315 0.71 BRD4 (0.38) KDM4EALDH1A1GAAKMT2ACYP1A2
SCHEMBL30293250 0.71 GSK3A (0.42) KDM4EALDH1A1GAAMAPTTSHR
SCHEMBL1352936 0.71 NOTUM (0.44) KDM4EALDH1A1MAPTHSD17B10TSHR
SCHEMBL31025720 0.69 MAOB (0.42) ALDH1A1TSHR
SCHEMBL29501063 0.67 FAAH (0.48) KDM4EALDH1A1KMT2AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113075182-A Portable device for measuring concentration of disinfectant 陈云秀 2021-07-06 CN disclosed
CN-106749004-A A kind of synthetic method of fluorescent molecular probe and the detection to chloride ion content in actual water sample 兰州大学 2017-05-31 CN disclosed