Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL15862264 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL3524266 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL4299694 | 0.76 | LMNA (0.52) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL8679882 | 0.76 | LMNA (0.67) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| Ethylene Glycol SCHEMBL2050406 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL19767750 | 0.73 | LMNA (0.73) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL8911477 | 0.73 | LMNA (0.53) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL1853865 | 0.72 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL10600208 | 0.72 | CAMK2A (0.37) | — | |
| SCHEMBL15158309 | 0.71 | LMNA (0.59) | SMN1; SMN2LMNAESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846021-B2 | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation | OLIGASIS, LLC (US) | 2014-09-30 | — | — | US | claimed |
| US-20220096643-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | KODIAK SCIENCES INC (US) | 2022-03-31 | — | — | US | disclosed |
| EP-1988910-B1 | ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION | KODIAK SCIENCES INC (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-3222142-A1 | ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION | Kodiak Sciences Inc. (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20150050714-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | OLIGASIS, LLC (US) | 2015-02-19 | — | — | US | disclosed |
| US-8846021-B2 | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation | OLIGASIS, LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130337534-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | OLIGASIS, LLC (US) | 2013-12-19 | — | — | US | disclosed |
| US-20100166700-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation | OLIGASIS CORPORATION (US) | 2010-07-01 | — | — | US | disclosed |
| EP-1988910-A2 | ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION | Oligasis Corporation (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007100905-A2 | ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION | NEXGEN THERAPEUTICS, LLC (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007100902-A2 | ACRYLOYLOXYETHYLPHOSPHORYLCHOLINE CONTAINING POLYMER CONJUGATES AND THEIR PREPARATION | OLIGASIS CORPORATION (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166700-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation | PHOSPHO1, PCTP, SGMS1 | SMN1; SMN2 1755/4885LMNA 1276/4885ESR1 4057/4885 |
| US-20220096643-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | PHOSPHO1, PCTP, SGMS1 | SMN1; SMN2 1755/4885LMNA 1276/4885ESR1 4057/4885 |
| US-20130337534-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | PHOSPHO1, PCTP, SGMS1 | SMN1; SMN2 1755/4885LMNA 1276/4885ESR1 4057/4885 |
| US-20150050714-A1 | Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation | PHOSPHO1, PCTP, SGMS1 | SMN1; SMN2 1755/4885LMNA 1276/4885ESR1 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.