Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300859 | 0.92 | GNAI3 (0.47) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4301850 | 0.79 | MEN1 (0.60) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4308322 | 0.77 | GNAI3 (0.53) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4306408 | 0.77 | GNAI3 (0.53) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4308311 | 0.77 | GNAI3 (0.53) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4304325 | 0.77 | GNAI3 (0.53) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4301981 | 0.76 | HPGD (0.48) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL4301970 | 0.76 | HPGD (0.48) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL9762648 | 0.74 | L3MBTL1 (0.88) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL13290614 | 0.73 | L3MBTL1 (0.85) | L3MBTL1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054398-A1 | NEW HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | Korea Research Institute of Bioscience and Biotechnology (KR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008018778-A1 | NEW HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-02-14 | — | — | WO | disclosed |