Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301981 | 1.00 | HPGD (0.48) | HPGDSMN1; SMN2L3MBTL1HRH2MEN1 | |
| SCHEMBL4307522 | 0.93 | CHRM1 (0.49) | HPGDSMN1; SMN2MAPTSIGMAR1ABL1 | |
| SCHEMBL4308949 | 0.93 | CHRM1 (0.49) | HPGDSMN1; SMN2MAPTSIGMAR1ABL1 | |
| SCHEMBL4030458 | 0.81 | HRH2 (0.54) | HPGDSMN1; SMN2HRH2MEN1KMT2A | |
| SCHEMBL4305129 | 0.81 | SIGMAR1 (0.48) | HPGDMEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL4301863 | 0.81 | SIGMAR1 (0.48) | HPGDMEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL4299821 | 0.76 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL14301937 | 0.75 | HTR7 (0.59) | HPGDSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4301850 | 0.75 | MEN1 (0.60) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL8210708 | 0.74 | HRH2 (0.50) | HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054398-A1 | NEW HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | Korea Research Institute of Bioscience and Biotechnology (KR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008018778-A1 | NEW HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN ATOMS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR TREATMENT OF CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2008-02-14 | — | — | WO | disclosed |