Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224078 | 0.92 | PTGS2 (0.35) | PTGS2 | |
| SCHEMBL3233652 | 0.91 | CXCR3 (0.32) | — | |
| SCHEMBL5257112 | 0.89 | CXCR3 (0.34) | PTGS2 | |
| SCHEMBL3233228 | 0.86 | CXCR3 (0.36) | — | |
| SCHEMBL3224069 | 0.83 | PTGS2 (0.35) | PTGS2 | |
| SCHEMBL3221968 | 0.82 | TRPA1 (0.37) | PTGS2 | |
| SCHEMBL3233029 | 0.81 | TDP1 (0.39) | PTGS2 | |
| SCHEMBL3216362 | 0.80 | CNR1 (0.38) | — | |
| SCHEMBL3230746 | 0.79 | TRPV1 (0.39) | PTGS2 | |
| SCHEMBL3229360 | 0.79 | CXCR3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2031965-A2 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147104-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |