SCHEMBL4300650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL408172	0.89	NPSR1 (0.60)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL408901	0.88	NPC1 (0.60)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL24303811	0.86	CA12 (0.56)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL408365	0.86	DGAT1 (0.59)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL4299394	0.86	DGAT1 (0.61)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL4298343	0.85	DGAT1 (0.67)	DGAT1NPC1RAB9ALMNAALDH1A1
	SCHEMBL22324675	0.85	DGAT1 (0.55)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL6178854	0.83	DGAT1 (0.51)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL408173	0.82	NPC1 (0.45)	NPSR1MAPK1DGAT1NPC1RAB9A
	SCHEMBL19795577	0.82	JUN (0.50)	NPSR1MAPK1DGAT1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.