Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.91 |
| ▸ | MAPT | P10636 | 4/20 | 0.91 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.91 |
| ▸ | MEN1 | O00255 | 4/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.91 |
| ▸ | HPGD | P15428 | 3/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.91 |
| ▸ | RECQL | P46063 | 3/20 | 0.91 |
| ▸ | TSHR | P16473 | 3/20 | 0.91 |
| ▸ | POLB | P06746 | 2/20 | 0.91 |
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.91 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.91 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.91 |
| ▸ | BCHE | P06276 | 1/20 | 0.91 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.91 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhein SCHEMBL25253 | 0.95 | ALDH1A1 (1.00) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL29404324 | 0.95 | ALDH1A1 (1.00) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL8012677 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23633120 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL1357918 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632879 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632868 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632984 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL1356821 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL526035 | 0.94 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831397-B | A kind of anthraquinone analog compound and preparation method thereof and medical application | 东北师范大学 | 2019-07-26 | — | — | CN | claimed |
| CN-106831397-A | A kind of anthraquinone analog compound and preparation method thereof and medical application | 东北师范大学 | 2017-06-13 | — | — | CN | claimed |
| CN-103025340-B | Aloe vera composition and its use in preparing medicaments for anti-viral and treating Acquired Immune Deficiency Syndrome (AIDS) | NORTH TEXAS MEDICAL ASS | 2014-12-24 | — | — | CN | claimed |
| CN-101786952-B | Anthraquinone compound and preparation method and medical application of lysine salt thereof | UNIV NORTHEAST NORMAL | 2013-11-06 | — | — | CN | claimed |
| EP-2595643-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | North Texas Medical Associates (US) | 2013-05-29 | — | — | EP | claimed |
| CN-103025340-A | Antiviral properties of Aloe vera and treatment of Acquired Immune Deficiency Syndrome (AIDS) | NORTH TEXAS MEDICAL ASS | 2013-04-03 | — | — | CN | claimed |
| US-20120022018-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | NORTH TEXAS MEDICAL ASSOCIATES (US) | 2012-01-26 | — | — | US | claimed |
| WO-2012012513-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | NORTH TEXAS MEDICAL ASSOCIATES (US) | 2012-01-26 | — | — | WO | claimed |
| CN-106831397-B | A kind of anthraquinone analog compound and preparation method thereof and medical application | 东北师范大学 | 2019-07-26 | — | — | CN | disclosed |
| CN-106831397-B | A kind of anthraquinone analog compound and preparation method thereof and medical application | 东北师范大学 | 2019-07-26 | — | — | CN | disclosed |
| CN-103025340-B | Aloe vera composition and its use in preparing medicaments for anti-viral and treating Acquired Immune Deficiency Syndrome (AIDS) | NORTH TEXAS MEDICAL ASS | 2014-12-24 | — | — | CN | disclosed |
| CN-101786952-B | Anthraquinone compound and preparation method and medical application of lysine salt thereof | UNIV NORTHEAST NORMAL | 2013-11-06 | — | — | CN | disclosed |
| EP-2595643-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | North Texas Medical Associates (US) | 2013-05-29 | — | — | EP | disclosed |
| CN-103025340-A | Antiviral properties of Aloe vera and treatment of Acquired Immune Deficiency Syndrome (AIDS) | NORTH TEXAS MEDICAL ASS | 2013-04-03 | — | — | CN | disclosed |
| US-20120022018-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | NORTH TEXAS MEDICAL ASSOCIATES (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012012513-A1 | ANTI-VIRAL PROPERTIES OF ALOE VERA AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) TREATMENT | NORTH TEXAS MEDICAL ASSOCIATES (US) | 2012-01-26 | — | — | WO | disclosed |
| CN-101786952-A | Anthraquinone compound and preparation method and medical application of lysine salt thereof | UNIV NORTHEAST NORMAL | 2010-07-28 | — | — | CN | disclosed |