Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080607 | 0.82 | CYP2D6 (0.42) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL6850946 | 0.80 | CYP2D6 (0.65) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL137568 | 0.76 | CYP2D6 (0.54) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3116027 | 0.75 | CYP2D6 (0.43) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL4292891 | 0.73 | MMP1 (0.37) | KMT2AMMP1MMP8ALDH1A1POLB | |
| SCHEMBL13589522 | 0.73 | CYP2D6 (0.56) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL10432669 | 0.73 | CYP2C19 (0.64) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL13588782 | 0.71 | CYP2D6 (0.54) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| SCHEMBL5001767 | 0.71 | CYP2D6 (0.54) | CYP2D6CYP2C19KMT2ANPC1RAB9A | |
| Potassium Ion SCHEMBL6327133 | 0.71 | CYP2D6 (0.54) | CYP2D6CYP2C19KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221571-A1 | HIV INTEGRASE INHIBITORS | MSD ITALIA S.R.L. (IT) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221571-A1 | HIV INTEGRASE INHIBITORS | TYMP, CDK2, TYMS | CYP2D6 762/4885CYP2C19 315/4885KMT2A 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.