SCHEMBL4301635

SCHEMBL4301635

Fc1cc(F)c(N(c2c(F)cc(F)cc2F)c2c(F)cc(F)cc2F)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.37
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.31
IDO1 P14902 1/20 0.30
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22067638 0.75 CES2 (0.37) ERN1CES2CES1ALDH1A1CA12
SCHEMBL7697369 0.75 ALDH1A1 (0.37) ERN1CES2CES1ALDH1A1CA12
SCHEMBL21279544 0.71 ALDH1A1 (0.33) ERN1CES2CES1ALDH1A1RAPGEF4
SCHEMBL78286 0.69 ERN1 (0.56) ERN1CES2CES1ALDH1A1CA12
SCHEMBL18387992 0.68 RIPK1 (0.36) ERN1ALDH1A1
SCHEMBL12578957 0.67 CES2 (0.39) ERN1CES2CES1ALDH1A1CA12
SCHEMBL531337 0.67 CES2 (0.52) ERN1CES2CES1ALDH1A1CA12
SCHEMBL4300027 0.67 CA1 (0.36) CES2CES1CA12CA1
SCHEMBL27540052 0.67 ERN1 (0.54) ERN1CES2CES1CA12CA1
SCHEMBL23252547 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7585590-B2 Rechargeable lithium-ion cell with triphenylamine redox shuttle 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-08 US claimed
EP-1994600-A2 RECHARGEABLE LITHIUM-ION CELL WITH TRIPHENYLAMINE REDOX SHUTTLE 3M Innovative Properties Company (US) 2008-11-26 EP claimed
WO-2007097912-A2 RECHARGEABLE LITHIUM-ION CELL WITH TRIPHENYLAMINE REDOX SHUTTLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-30 WO claimed
US-20070196727-A1 Rechargeable Lithium-Ion Cell with Triphenylamine Redox Shuttle 3M INNOVATIVE PROPERTIES COMPANY 2007-08-23 US claimed