Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 5/20 | 0.36 |
| ▸ | FNTB | P49356 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289440 | 0.82 | CYP11B2 (0.37) | CYP11B2ADORA1KDM4EALDH1A1HTT | |
| SCHEMBL4292396 | 0.81 | ELANE (0.44) | KDM4EALDH1A1HTTKMT2ACNR1 | |
| SCHEMBL4285897 | 0.79 | KMO (0.51) | ALDH1A1L3MBTL1HSD17B10MEN1CYP1A2 | |
| SCHEMBL4295762 | 0.75 | PTGER4 (0.36) | FNTAFNTBKDM4EALDH1A1MEN1 | |
| SCHEMBL15997886 | 0.74 | CYP11B2 (0.48) | CYP11B2KDM4EL3MBTL1HSD17B10NR4A2 | |
| SCHEMBL15987446 | 0.74 | CYP11B2 (0.48) | CYP11B2ADORA1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL15999081 | 0.74 | CYP11B2 (0.46) | CYP11B2ADORA1KDM4EHSD17B10NR4A2 | |
| SCHEMBL15999037 | 0.73 | CYP11B2 (0.47) | CYP11B2KDM4EL3MBTL1HSD17B10NR4A2 | |
| SCHEMBL4289100 | 0.73 | KMT2A (0.54) | KDM4EALDH1A1HTTMEN1CYP1A2 | |
| SCHEMBL4292497 | 0.73 | KMO (0.49) | KDM4EALDH1A1MCHR1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | CYP11B2 6/4885FNTA 1157/4885FNTB 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.