Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746466 | 0.90 | ACP1 (0.52) | SMN1; SMN2HTTKMT2AALDH1A1ACP1 | |
| SCHEMBL4939716 | 0.86 | DYRK1A (0.61) | SMN1; SMN2HTTKMT2APDK1DYRK1A | |
| SCHEMBL20764179 | 0.82 | MAPT (0.64) | SMN1; SMN2KMT2AALDH1A1CYP3A4CA2 | |
| SCHEMBL4301852 | 0.82 | KMT2A (0.54) | SMN1; SMN2HTTKMT2ADYRK1AALDH1A1 | |
| SCHEMBL17038164 | 0.81 | PTPN1 (0.59) | SMN1; SMN2KMT2ADYRK1AALDH1A1ACP1 | |
| SCHEMBL9798029 | 0.81 | DYRK1A (0.65) | SMN1; SMN2HTTKMT2APDK1DYRK1A | |
| SCHEMBL13805533 | 0.80 | HSD17B1 (0.55) | SMN1; SMN2CYP3A4MAPTMAOBSTAT1 | |
| SCHEMBL17038135 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1CA2MAPT | |
| SCHEMBL4940843 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTKMT2APDK1DYRK1A | |
| SCHEMBL11161571 | 0.80 | KMT2A (0.73) | SMN1; SMN2HTTKMT2ADYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586759-B2 | Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2013-11-19 | — | — | US | claimed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | claimed |
| US-8586759-B2 | Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2013-11-19 | — | — | US | disclosed |
| US-8586759-B2 | Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | disclosed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | disclosed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| EP-1954132-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007100758-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | HCCS, HLCS, GLUL | SMN1; SMN2 4724/4885HTT 3672/4885KMT2A 4121/4885 |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | HCCS, HLCS, GLUL | SMN1; SMN2 4724/4885HTT 3672/4885KMT2A 4121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.