SCHEMBL430246

SCHEMBL430246

CC1(C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(-c3ccc4cc(-c5ccc6ccccc6c5)ccc4c3)cc21

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.70
LPL P06858 8/20 0.70
DGAT1 O75907 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SNCA P37840 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.36
PTGER3 P43115 4/20 0.35
GSTP1 P09211 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CYP17A1 P05093 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12056858 1.00 LIPG (0.70) LIPGLPLDGAT1CA1CA2
SCHEMBL431654 1.00 LIPG (0.70) LIPGLPLDGAT1CA1CA2
SCHEMBL30166961 1.00 LIPG (0.70) LIPGLPLDGAT1CA1CA2
SCHEMBL15678316 0.91 LIPG (0.61) LIPGLPLDGAT1CA1CA2
SCHEMBL12056857 0.91 LIPG (0.60) LIPGLPLDGAT1CA1CA2
SCHEMBL431655 0.91 LIPG (0.60) LIPGLPLDGAT1CA1CA2
SCHEMBL15678313 0.90 LIPG (0.59) LIPGLPLDGAT1CA1CA2
SCHEMBL1753517 0.89 LIPG (0.50) LIPGLPLDGAT1CA1CA2
SCHEMBL431646 0.88 LIPG (0.51) LIPGLPLDGAT1CA1CA2
SCHEMBL430244 0.88 LIPG (0.51) LIPGLPLDGAT1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed