SCHEMBL431646

SCHEMBL431646

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(B5OC(C)(C)C(C)(C)O5)ccc3-4)cc21

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.51
LPL P06858 9/20 0.51
DGAT1 O75907 1/20 0.38
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
PDK2 Q15119 5/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
PDGFRB P09619 1/20 0.34
KDR P35968 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430244 1.00 LIPG (0.51) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL1753909 0.94 LIPG (0.59) LIPGLPLDGAT1PDK2CA1
SCHEMBL29450660 0.94 LPL (0.49) LIPGLPLPRMT5WDR77CA1
SCHEMBL70348 0.94 LPL (0.49) LIPGLPLPRMT5WDR77CA1
SCHEMBL29674722 0.94 LPL (0.49) LIPGLPLPRMT5WDR77CA1
SCHEMBL15298700 0.93 LIPG (0.48) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL1753517 0.93 LIPG (0.50) LIPGLPLDGAT1CA1CA2
SCHEMBL12056857 0.92 LIPG (0.60) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL431655 0.92 LIPG (0.60) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL12127168 0.92 LIPG (0.49) LIPGLPLPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639339-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-05-02 US disclosed
US-11639339-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-05-02 US disclosed
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
US-11365167-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-06-21 US disclosed
EP-3792235-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2021-03-17 EP disclosed
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-25 US disclosed
EP-3481796-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-17 EP disclosed
US-20210024481-A1 MATERIALS FOR ORGANIC ELETROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-28 US disclosed
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-07 US disclosed
US-20200369678-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-11-26 US disclosed
US-7704609-B2 Compound and organic electroluminescense device using the same CANON KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed
US-20100019661-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2009-11-12 US disclosed
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2009-11-12 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
EP-2045231-A1 Binaphthyl compound and organic light emitting element using the same Canon Kabushiki Kaisha (JP) 2009-04-08 EP disclosed
US-20080161574-A1 DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-07-03 US disclosed
US-20080161574-A1 DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-07-03 US disclosed
WO-2008015945-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024481-A1 MATERIALS FOR ORGANIC ELETROLUMINESCENT DEVICES GLB1, EFNA1, L1CAM LIPG 510/4885LPL 1778/4885DGAT1 2953/4885
US-11639339-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME ALPL, MT-ND4L, LAGE3 LIPG 2208/4885LPL 1254/4885DGAT1 926/4885
US-20080161574-A1 DIAZAFLUORENE COMPOUND AFF1, NPFFR1, AFF2 LIPG 4352/4885LPL 4328/4885DGAT1 898/4885
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND FOXK1, KCNK10, F10 LIPG 1545/4885LPL 550/4885DGAT1 3079/4885
US-20100019661-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME AFF1, AFF2, CYP1A1 LIPG 3239/4885LPL 3223/4885DGAT1 3014/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 LIPG 2692/4885LPL 3880/4885DGAT1 1504/4885
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-11365167-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-20200369678-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.