SCHEMBL1753517

SCHEMBL1753517

CC1(C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(B5OC(C)(C)C(C)(C)O5)ccc3-4)cc21

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.50
LPL P06858 13/20 0.50
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
SNCA P37840 1/20 0.36
DGAT1 O75907 1/20 0.36
F11 P03951 1/20 0.36
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12781865 0.97 LIPG (0.56) LIPGLPLCA1CA2CA9
SCHEMBL70387 0.93 LIPG (0.59) LIPGLPLCA1CA2CA9
SCHEMBL69358 0.93 LIPG (0.47) LIPGLPLCA1CA2CA9
SCHEMBL429991 0.93 LIPG (0.64) LIPGLPLCA1CA2CA9
SCHEMBL431646 0.93 LIPG (0.51) LIPGLPLCA1CA2CA9
SCHEMBL430244 0.93 LIPG (0.51) LIPGLPLCA1CA2CA9
SCHEMBL19612784 0.90 LIPG (0.46) LIPGLPLCA1CA2CA9
SCHEMBL16435209 0.90 LIPG (0.44) LIPGLPLCA1CA2CA9
SCHEMBL69840 0.89 LIPG (0.50) LIPGLPLCA1CA2CA9
SCHEMBL12056858 0.89 LIPG (0.70) LIPGLPLCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481175-B2 Oligofluorene compound and organic EL element using same CANON KABUSHIKI KAISHA (JP) 2013-07-09 US disclosed
US-8481175-B2 Oligofluorene compound and organic EL element using same CANON KABUSHIKI KAISHA (JP) 2013-07-09 US disclosed
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed
US-8158835-B2 Fluorene compound and organic electroluminescence device CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-8158835-B2 Fluorene compound and organic electroluminescence device CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-07 US disclosed
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AFF1, LEF1, AFF2 LIPG 2072/4885LPL 1917/4885CA1 2732/4885
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AFF1, LEF1, AFF2 LIPG 2072/4885LPL 1917/4885CA1 2732/4885
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME ELP1, LEF1, ELAVL1 LIPG 2759/4885LPL 2134/4885CA1 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.