Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318894 | 0.88 | MEN1 (0.45) | MASP2NAMPT | |
| SCHEMBL4309387 | 0.85 | NAMPT (0.44) | MASP2NAMPTFURIN | |
| SCHEMBL4310295 | 0.84 | CYP2C9 (0.46) | EPHX2MASP2NAMPT | |
| SCHEMBL4313762 | 0.84 | NAMPT (0.56) | MASP2NAMPT | |
| SCHEMBL4303439 | 0.84 | NAMPT (0.53) | EPHX2MASP2NAMPT | |
| SCHEMBL4312613 | 0.84 | SMN1; SMN2 (0.45) | MASP2ALDH1A1HTTNAMPT | |
| SCHEMBL4309246 | 0.83 | MEN1 (0.43) | EPHX2NR1H4MASP2LMNANAMPT | |
| SCHEMBL3139988 | 0.82 | MASP2 (0.48) | EPHX2NR1H4MASP2ALDH1A1LMNA | |
| SCHEMBL4318995 | 0.82 | NAMPT (0.49) | EPHX2MASP2ALDH1A1LMNANAMPT | |
| SCHEMBL4305726 | 0.79 | NAMPT (0.45) | MASP2NAMPTFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |