Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312613 | 0.90 | SMN1; SMN2 (0.45) | MEN1KMT2AMASP2POLBNPC1 | |
| SCHEMBL4309387 | 0.84 | NAMPT (0.44) | MASP2NAMPT | |
| SCHEMBL4310295 | 0.83 | CYP2C9 (0.46) | MEN1KMT2AMASP2RAB9AEPHX2 | |
| SCHEMBL4313762 | 0.83 | NAMPT (0.56) | MEN1KMT2AMASP2NAMPT | |
| SCHEMBL4303439 | 0.83 | NAMPT (0.53) | MEN1KMT2AMASP2POLBEPHX2 | |
| SCHEMBL4303085 | 0.83 | EPHX2 (0.44) | LMNAMASP2EPHX2NR1H4NAMPT | |
| SCHEMBL3144606 | 0.83 | MASP2 (0.47) | MEN1KMT2ALMNAMAPK1MASP2 | |
| SCHEMBL4318995 | 0.81 | NAMPT (0.49) | LMNAMASP2EPHX2NAMPT | |
| SCHEMBL4318894 | 0.81 | MEN1 (0.45) | MEN1KMT2AMASP2POLBNAMPT | |
| SCHEMBL4304420 | 0.79 | MEN1 (0.47) | MEN1KMT2ALMNAMASP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |