Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | MASP2 | O00187 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303439 | 0.93 | NAMPT (0.53) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4309387 | 0.86 | NAMPT (0.44) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4313762 | 0.85 | NAMPT (0.56) | NAMPTMASP2GABRPGABRDGABRA1 | |
| SCHEMBL4310295 | 0.85 | CYP2C9 (0.46) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4312613 | 0.82 | SMN1; SMN2 (0.45) | NAMPTMASP2ALDH1A1 | |
| SCHEMBL4303085 | 0.82 | EPHX2 (0.44) | NAMPTMASP2LMNAEPHX2ALDH1A1 | |
| SCHEMBL4318894 | 0.82 | MEN1 (0.45) | NAMPTMASP2HDAC1 | |
| SCHEMBL3157855 | 0.82 | MASP2 (0.53) | NAMPTMASP2BACE1BACE2GABRP | |
| SCHEMBL4309246 | 0.81 | MEN1 (0.43) | NAMPTMASP2LMNAEPHX2 | |
| SCHEMBL3154097 | 0.81 | MMP8 (0.52) | NAMPTMASP2BACE1BACE2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |