Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874875 | 0.70 | KDM4E (0.52) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL14148998 | 0.67 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL27341471 | 0.67 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3470444 | 0.66 | KDM4E (0.58) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4409938 | 0.65 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6183937 | 0.65 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL4099271 | 0.64 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4099273 | 0.64 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15450912 | 0.63 | ALDH1A1 (0.60) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL119513 | 0.63 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |