Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409938 | 0.73 | ALDH1A1 (0.54) | KDM4EALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL14148998 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL11742759 | 0.72 | KCNH2 (0.48) | KDM4EALDH1A1HPGDRAB9AMAPK1 | |
| SCHEMBL3470444 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL12501247 | 0.70 | LMNA (0.54) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL4303568 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL6183937 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL4099271 | 0.69 | KDM4E (0.66) | KDM4EALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL4099273 | 0.69 | KDM4E (0.66) | KDM4EALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL21055815 | 0.68 | APP (0.59) | KDM4EALDH1A1HPGDRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045922-B | 2- (amino) methylquinazolin -4 (3H) -one class compound and its preparation method and application | XIANGTAN UNIVERSITY (CN) | 2019-07-16 | — | — | CN | disclosed |