Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307360 | 0.84 | EGLN1 (0.67) | MAPTSMN1; SMN2EGLN1FAAHHDAC3 | |
| SCHEMBL24450206 | 0.82 | HDAC3 (0.58) | MAPTSMN1; SMN2FAAHHDAC3HDAC1 | |
| SCHEMBL1233153 | 0.82 | HDAC3 (0.54) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL4304567 | 0.82 | EGLN1 (0.60) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL28377716 | 0.80 | HDAC3 (0.65) | ALDH1A1SMN1; SMN2FAAHHDAC3HDAC1 | |
| SCHEMBL1221009 | 0.80 | HDAC3 (0.58) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL6542084 | 0.80 | FAAH (0.55) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL4069991 | 0.78 | LMNA (0.57) | SMN1; SMN2HPGDFAAHHDAC3HDAC1 | |
| SCHEMBL8594130 | 0.78 | HDAC3 (0.60) | ALDH1A1SMN1; SMN2FAAHHDAC3HDAC1 | |
| SCHEMBL7423976 | 0.77 | SMYD3 (0.58) | KDM4EALDH1A1MAPTSMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284335-A1 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-10-08 | — | — | US | disclosed |
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284335-A1 | Benzoimidazoles as prolyl hydroxylase inhibitors | EGLN3, EGLN2, P4HA1 | KDM4E 424/4885ALDH1A1 156/4885MAPT 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.