SCHEMBL4304192

SCHEMBL4304192

COC(=O)C(C)(C)CC(C)(Br)C(=O)OC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.37
KCNN4 O15554 1/20 0.33
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SRC P12931 1/20 0.31
PRSS1 P07477 1/20 0.30
CTSG P08311 1/20 0.30
CTRB1 P17538 1/20 0.30
CMA1 P23946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998983 0.86 CYP4F2 (0.43) KMT2ASMN1; SMN2
SCHEMBL8209508 0.84 DGAT1 (0.38) DGAT1KCNN4LMNAKMT2ASMN1; SMN2
SCHEMBL17549708 0.83 CYP4F2 (0.34)
SCHEMBL17574065 0.83 DGAT1 (0.44) DGAT1KCNN4SRCPRSS1CTSG
SCHEMBL9906787 0.82
SCHEMBL12050490 0.80 CYP3A4 (0.34) KMT2A
SCHEMBL13625044 0.79 ABCB11 (0.35)
SCHEMBL17904754 0.79 CHRM2 (0.41) LMNASMN1; SMN2
SCHEMBL14959853 0.78 DGAT1 (0.34) DGAT1KCNN4
SCHEMBL786780 0.78 DGAT1 (0.41) DGAT1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7579401-B2 Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries NIPPON SODA CO., LTD. (JP) 2009-08-25 US disclosed
US-20070270521-A1 Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2007-11-22 US disclosed
EP-1553117-B1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO (JP) 2007-01-17 EP disclosed
US-20050256256-A1 Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries NIPPON SODA CO., LTD (JP) 2005-11-17 US disclosed
EP-1553117-A1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO., LTD. (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270521-A1 Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer CARM1, CPN1, CCNT1 DGAT1 4163/4885KCNN4 1786/4885LMNA 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.