Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684458 | 0.89 | NAALAD2 (0.66) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL9439238 | 0.89 | NAALAD2 (0.66) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL20836770 | 0.89 | NAALAD2 (0.66) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL1323164 | 0.89 | NAALAD2 (0.66) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL3770150 | 0.86 | ACE (0.60) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL12122453 | 0.85 | CTSS (0.64) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL1273042 | 0.85 | CTSS (0.64) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL4304262 | 0.84 | KLK5 (0.59) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL4347053 | 0.84 | KLK5 (0.59) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL4304252 | 0.84 | KLK5 (0.59) | ACECTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |