Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 5/20 | 0.58 |
| ▸ | PPARG | P37231 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 2/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20836770 | 0.91 | NAALAD2 (0.66) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL9439238 | 0.91 | NAALAD2 (0.66) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL8684458 | 0.91 | NAALAD2 (0.66) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL1323164 | 0.91 | NAALAD2 (0.66) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL4304258 | 0.86 | ACE (0.57) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL2173588 | 0.84 | REN (0.67) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL4420859 | 0.84 | REN (0.67) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL7618822 | 0.84 | REN (0.67) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL66220 | 0.84 | ACE (0.79) | ACEPPARAPPARGCTSSCTSK | |
| SCHEMBL606309 | 0.84 | ACE (0.79) | ACEPPARAPPARGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851449-B2 | Peptide, pharmaceutical composition, and a method of treating microcirculation disorders | Obschestvo S Ogranichennoi Otvetstvennostyu “SIA Peptides” (RU) | 2010-12-14 | — | — | US | disclosed |
| EP-2024387-B1 | PEPTIDE SUBSTANCE ENHANCING CAPILLARIES RESISTANCE, PHARMACEUTICAL COMPOSITION ON ITS BASE AND METHOD OF ITS APPLICATION | OBSCHESTVO S OGRANICHENNOI OTV (RU) | 2009-10-21 | — | — | EP | disclosed |
| US-20090099098-A1 | PEPTIDE SUBSTANCE ENHANCING CAPILLARIES RESISTANCE, PHARMACEUTICAL COMPOSITION ON ITS BASE AND METHOD OF ITS APPLICATION | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU "SIA PEPTIDES" (RU) | 2009-04-16 | — | — | US | disclosed |
| EP-2024387-A1 | PEPTIDE SUBSTANCE ENHANCING CAPILLARIES RESISTANCE, PHARMACEUTICAL COMPOSITION ON ITS BASE AND METHOD OF ITS APPLICATION | Obschestvo S Ogranichennoi Otvetstvennostyu "sia Peptides" (RU) | 2009-02-18 | — | — | EP | disclosed |
| US-7442788-B2 | Antisense molecules and method of controlling expression of gene function by using the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| WO-2007136294-A1 | PEPTIDE SUBSTANCE ENHANCING CAPILLARIES RESISTANCE, PHARMACEUTICAL COMPOSITION ON ITS BASE AND METHOD OF ITS APPLICATION | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU 'SIA PEPTIDES' (RU) | 2007-11-29 | — | — | WO | disclosed |
| US-6872809-B2 | Nucleoside derivatives | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20030208050-A1 | Nucleoside derivatives | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-11-06 | — | — | US | disclosed |
| US-20030162739-A1 | Antisense molecules and method of controlling expression of gene function by using the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1295892-A1 | ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME | Japan Science and Technology Corporation (JP) | 2003-03-26 | — | — | EP | disclosed |
| EP-1295891-A1 | NUCLEOSIDE DERIVATIVES | Japan Science and Technology Corporation (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162739-A1 | Antisense molecules and method of controlling expression of gene function by using the same | RNGTT, RNMT, UPF1 | ACE 4328/4885PPARA 3638/4885PPARG 2555/4885 |
| US-20030208050-A1 | Nucleoside derivatives | RIMKLA, MTHFD1, AADAT | ACE 3230/4885PPARA 4053/4885PPARG 3739/4885 |
| US-20090099098-A1 | PEPTIDE SUBSTANCE ENHANCING CAPILLARIES RESISTANCE, PHARMACEUTICAL COMPOSITION ON ITS BASE AND METHOD OF ITS APPLICATION | VIP, ASNS, FLT1 | ACE 391/4885PPARA 3584/4885PPARG 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.