Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304330 | 0.84 | CREBBP (0.40) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4304338 | 0.81 | MEN1 (0.35) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4308381 | 0.72 | ALDH1A1 (0.47) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4311027 | 0.71 | CREBBP (0.41) | CREBBPEP300MEN1KMT2AALDH1A1 | |
| SCHEMBL4309447 | 0.68 | CREBBP (0.59) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4683757 | 0.67 | MEN1 (0.48) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4311192 | 0.66 | CREBBP (0.44) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4321067 | 0.64 | CREBBP (0.40) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4315290 | 0.64 | CREBBP (0.58) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL3645168 | 0.63 | CREBBP (0.52) | CREBBPEP300MEN1KMT2AICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |