Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311026 | 0.82 | CREBBP (0.47) | CREBBPMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL4311031 | 0.80 | MEN1 (0.40) | CREBBPMEN1KMT2AEP300ADORA3 | |
| SCHEMBL4313090 | 0.77 | TSHR (0.49) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1547662 | 0.77 | TSHR (0.51) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL4317064 | 0.76 | TSHR (0.50) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL4456107 | 0.76 | TSHR (0.46) | CREBBPMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL4308381 | 0.76 | ALDH1A1 (0.47) | CREBBPMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL4312331 | 0.73 | CREBBP (0.52) | CREBBPMEN1KMT2ATSHRTP53 | |
| Tetrahydrofuran SCHEMBL28198630 | 0.72 | KAT8 (0.53) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL4304334 | 0.71 | CREBBP (0.35) | CREBBPMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |