Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310838 | 0.77 | APP (0.41) | ALDH1A1KDM4EHTR1ADRD2HTR2A | |
| SCHEMBL3574877 | 0.73 | — | — | |
| SCHEMBL5474386 | 0.71 | ALDH1A1 (0.33) | ALDH1A1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL7206090 | 0.69 | — | — | |
| SCHEMBL10396090 | 0.68 | HTR1A (0.48) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10396554 | 0.68 | HTR1A (0.48) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL20250954 | 0.68 | HTR1A (0.48) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL2263006 | 0.68 | APLNR (0.32) | — | |
| SCHEMBL1164326 | 0.68 | APLNR (0.32) | — | |
| SCHEMBL6999896 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473752-B2 | Functionalized silicone resins, methods for their preparation, and use as catalysts | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-01-06 | — | — | US | disclosed |
| US-20070135661-A1 | Functionalized silicone resins, methods for their preparation, and use as catalysts | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-06-14 | — | — | US | disclosed |
| US-7193027-B2 | Functionalized silicone resins, methods for their preparation, and use as catalysts | GENERAL ELECTRIC COMPANY (US) | 2007-03-20 | — | — | US | disclosed |
| WO-2005016996-A1 | FUNCTIONALIZED SILICONE RESINS, METHODS FOR THEIR PREPARATION, AND USE AS CATALYSTS | GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050033002-A1 | Functionalized silicone resins, methods for their preparation, and use as catalysts | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135661-A1 | Functionalized silicone resins, methods for their preparation, and use as catalysts | ESR1, MUS81, C1R | ALDH1A1 2285/4885KDM4E 1049/4885HTR1A 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.