Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301270 | 0.83 | SLC18A3 (0.48) | OPRL1OPRM1OPRK1KDRALK | |
| Hydrochloric Acid SCHEMBL5720133 | 0.81 | HPGD (0.40) | KDRALKTLR9TLR7TLR8 | |
| SCHEMBL5720125 | 0.79 | CHRM1 (0.41) | ALDH1A1TLR9TLR7TRPV6TLR8 | |
| SCHEMBL5720092 | 0.76 | CHRM1 (0.51) | ALDH1A1TRPV6MEN1KMT2A | |
| SCHEMBL6215486 | 0.75 | OPRL1 (0.40) | OPRL1OPRM1OPRK1CYP2C9KDR | |
| SCHEMBL5720388 | 0.75 | DRD2 (0.40) | OPRK1TLR9TLR7TRPV6TLR8 | |
| SCHEMBL5720279 | 0.74 | DRD2 (0.41) | ALDH1A1TLR9TLR7TRPV6TLR8 | |
| SCHEMBL5720129 | 0.74 | TLR9 (0.35) | ALDH1A1TLR9TLR7TRPV6TLR8 | |
| SCHEMBL5720269 | 0.74 | DRD2 (0.39) | ALKALDH1A1TLR9TLR7TRPV6 | |
| SCHEMBL5720385 | 0.74 | CHRM1 (0.53) | ALDH1A1TRPV6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |