Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305741 | 0.75 | OPRL1 (0.43) | OPRL1OPRM1OPRK1IKZF2KDR | |
| SCHEMBL6210565 | 0.74 | DRD2 (0.48) | IKZF2ALDH1A1TLR9TLR7TLR8 | |
| SCHEMBL6210841 | 0.71 | PIK3CA (0.41) | OPRM1KDRALKCYP2C9IGF1R | |
| SCHEMBL6212055 | 0.71 | ACHE (0.48) | OPRL1OPRM1MEN1KMT2A | |
| SCHEMBL6212405 | 0.69 | MEN1 (0.35) | KDRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6212065 | 0.67 | NPC1 (0.48) | OPRL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1863063 | 0.67 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1863062 | 0.67 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL10992847 | 0.67 | MEN1 (0.44) | OPRL1OPRM1OPRK1KDRALK | |
| SCHEMBL10992849 | 0.67 | MEN1 (0.44) | OPRL1OPRM1OPRK1KDRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379246-A4 | NOCICEPTIN ANALOGS | EURO CELTIQUE SA (LU) | 2005-09-28 | — | — | EP | claimed |
| EP-1379246-A1 | NOCICEPTIN ANALOGS | Euro-Celtique S.A. (LU) | 2004-01-14 | — | — | EP | claimed |
| WO-2002085357-A1 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| EP-1379246-A4 | NOCICEPTIN ANALOGS | EURO CELTIQUE SA (LU) | 2005-09-28 | — | — | EP | disclosed |
| EP-1379246-A1 | NOCICEPTIN ANALOGS | Euro-Celtique S.A. (LU) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002085357-A1 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | disclosed |